WEB-ENABLED 3D MULTIMODALITY BRAIN VISUALIZATION IN JAVA E.B.Moore1; A.Poliakov1*; J.F.Brinkley1,2,3 1. Structural Informatics Group, Dept. of Biol. Structure, 2. Med. Edu.and Biomedical Informatics, 3. Comp. Sci. and Eng., Univ. of Washington, Seattle, WA, USA Brain imaging data come from many sources (MRI, EEG, etc.) and may represent a result of complex analyses (fMRI statistics, connectivity data, vector and tensor fields, etc.). Some data are time-dependent and some are difficult to visualize. There is therefore a need to combine various data modalities and visualize them on the same brain to see how they interrelate. BrainJ3D is our visualization software that addresses this need by allowing users to visualize 2D, 3D, and snapshots in time of 4D data. BrainJ3D is cross-platform, utilizes the hardware accelerated Java3D API, and has an extensible architecture so plug-ins can easily be added to accommodate new data sources and novel visualization techniques. BrainJ3D imports data from several popular analysis software packages, including SPM, FSL etc. The data are organized by category in a coherent and flexible XML workspace that keeps the relevant data accessible. There are 2 major views: 1) a slice viewer for axial images from 3D or 4D image volumes and 2) an interactive 3D viewer of surfaces, points and volumes. The slice viewer allows the user to overlay many types of structural and functional data at once. In the 3D view, the user interacts with cortical and other surfaces from individual subjects. Users can also cut the surface to see slices of deep structures. The 3D mapping feature allows the user to measure the coordinates of interesting locations, create points and label them. BrainJ3D has a web-enabled version with a thin client and a visualization server, which makes it suitable for remote visualization as an aid to collaboration and data sharing. The software is currently being used primarily for language studies that involve fMRI and cortical stimulation mapping during surgery. Another group studying autism uses BrainJ3D to visualize 4D ERP data and fMRI. BrainJ3D will be released and publicly available from http://sig.biostr.washington.edu/projects/brainj3d. Support Contributed By: Human Brain Project grant MH/DC02310. Citation:E.B. Moore, A. Poliakov, J.F. Brinkley. WEB-ENABLED 3D MULTIMODALITY BRAIN VISUALIZATION IN JAVA Program No. 570.2. 2005 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. Online.