On carcinomas and other pathological entities

Smith, Barry and Kumar, Anand and Ceusters, Werner and Rosse, Cornelius (2005) On carcinomas and other pathological entities. Comparative and Functional Genomics, 6 (7-8). pp. 379-387.

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Abstract

Tumours, abscesses, cysts, scars and fractures are familiar types of what we shall
call pathological continuant entities. The instances of such types exist always in
or on anatomical structures, which thereby become transformed into pathological
anatomical structures of corresponding types: a fractured tibia, a blistered thumb, a
carcinomatous colon. In previous work on biomedical ontologies we showed how the
provision of formal definitions for relations such as is a, part of and transformation
of can facilitate the integration of such ontologies in ways which have the potential
to support new kinds of automated reasoning. We here extend this approach to the
treatment of pathologies, focusing especially on those pathological continuant entities
which arise when organs become affected by carcinomas. Copyright � 2006 John
Wiley & Sons, Ltd.

Item Type: Article
Uncontrolled Keywords: ontology, pathology, anatomy, cancer staging, carcinoma, pathogenesis
Subjects: All Projects > Foundational Model of Anatomy
Depositing User: Jim Brinkley
Date Deposited: 20 Jun 2007
Last Modified: 20 Jul 2017 00:34
URI: http://sigpubs.si.washington.edu/id/eprint/208

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