Using multiple reference ontologies: Managing composite annotations

Gennari, John H and Neal, Maxwell L and Mejino, Jose L V and Cook, Daniel L (2009) Using multiple reference ontologies: Managing composite annotations. In: International Conference on Biomedical Ontology. pp. 83-86.

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There are a growing number of reference ontologies available across a variety of biomedical domains and current research focuses on their construction, organization and use. An important use case for these ontologies is annotation�where users create metadata that access concepts and terms in reference ontologies. We draw on our experience in physiological modeling to present a compelling use case that demonstrates the potential complexity of such annotations. In the domain of physiological biosimulation, we argue that most annotations require the use of multiple reference ontologies. We suggest that these �composite� annotations should be retained as a repository of knowledge about post-coordination that promotes sharing and interoperation across biosimulation models.

Item Type: Book Section
Subjects: All Projects > Biosimulation
Depositing User: Jim Brinkley
Date Deposited: 26 Feb 2010
Last Modified: 24 Jul 2017 23:41

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