A Reference Ontology for Bioinformatics: The Foundational Model of Anatomy

Rosse, Cornelius and Mejino, Jose L V (2003) A Reference Ontology for Bioinformatics: The Foundational Model of Anatomy. Journal of Biomedical Informatics, 36. pp. 478-500.

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Abstract

The Foundational Model of Anatomy (FMA), initially developed as an enhancement of the anatomical content of UMLS, is a domain ontology of the concepts and relationships that pertain to the structural organization of the human body. It encompasses the material objects from the molecular to the macroscopic levels that constitute the body and associates with them nonmaterial entities (spaces, surfaces, lines and points) required for describing structural relationships. The disciplined modeling approach employed for the development of the FMA relies on a set of declared principles, high level schemes, Aristotelian definitions and a frame-based authoring environment. We propose the FMA as a reference ontology in biomedical informatics for correlating different views of anatomy, aligning existing and emerging ontologies in bioinformatics and providing a structure-based template for representing biological functions.

Item Type: Article
Uncontrolled Keywords: ontology, knowledge representation, anatomy, mereotopology, embryology, developmental biology
Subjects: All Projects > Foundational Model of Anatomy
Depositing User: Jim Brinkley
Date Deposited: 04 Aug 2003
Last Modified: 19 Jul 2017 03:48
URI: http://sigpubs.si.washington.edu/id/eprint/135

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