Evolution of a Foundational Model of Physiology: Symbolic Representation for Functional Bioinformatics

Cook, Daniel L and Mejino, Jose L V and Rosse, Cornelius (2004) Evolution of a Foundational Model of Physiology: Symbolic Representation for Functional Bioinformatics. In: MedInfo 2004. pp. 336-340.

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Abstract

We describe the need for a Foundational Model of Physiology (FMP) as a reference ontology for functional bioinformatics . The FMP is intended to support symbolic lookup, logical inference and mathematical analysis by integrating descriptive, qualitative and quantitative functional knowledge. The FMP will serve as a symbolic representation of biological functions initially pertaining to human physiology and ultimately extensible to other species. We describe the evolving architecture of the FMP, which is based on the ontological principles of the BioD biological description language and the Foundational Model of Anatomy (FMA).

Item Type: Book Section
Uncontrolled Keywords: functional bioinformatics, knowledge representation, ontology, physiology, virtual human, computational modeling, medinfo2004
Subjects: All Projects > Biosimulation
Depositing User: Jim Brinkley
Date Deposited: 21 Oct 2004
Last Modified: 25 Jul 2017 22:30
URI: http://sigpubs.si.washington.edu/id/eprint/161

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