The FaceBase Consortium: a comprehensive resource for craniofacial researchers

Brinkley, James F and Fisher, Shannon and Harris, Matthew P. and Holmes, Greg and Hooper, Joan E. and Wang Jabs, Ethylin and Jones, Kenneth L. and Kesselman, Carl and Klein, Ophir D. and Maas, Richard L. and Marazita, Mary L. and Selleri, Licia and Spritz, Richard A. and van Bakel, Harm and Visel, Axel and Williams, Trevor J. and Wysocka, Joanna and Chai, Yang (2016) The FaceBase Consortium: a comprehensive resource for craniofacial researchers. Development, 143 (14). pp. 2677-2688. ISSN 0950-1991

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The FaceBase Consortium, funded by the National Institute of Dental and Craniofacial Research, National Institutes of Health, is designed to accelerate understanding of craniofacial developmental biology by generating comprehensive data resources to empower the research community, exploring high-throughput technology, fostering new scientific collaborations among researchers and human/computer interactions, facilitating hypothesis-driven research and translating science into improved health care to benefit patients. The resources generated by the FaceBase projects include a number of dynamic imaging modalities, genome-wide association studies, software tools for analyzing human facial abnormalities, detailed phenotyping, anatomical and molecular atlases, global and specific gene expression patterns, and transcriptional profiling over the course of embryonic and postnatal development in animal models and humans. The integrated data visualization tools, faceted search infrastructure, and curation provided by the FaceBase Hub offer flexible and intuitive ways to interact with these multidisciplinary data. In parallel, the datasets also offer unique opportunities for new collaborations and training for researchers coming into the field of craniofacial studies. Here, we highlight the focus of each spoke project and the integration of datasets contributed by the spokes to facilitate craniofacial research.

Item Type: Article
Subjects: All Projects > Ontology of Craniofacial Development and Malformation
Depositing User: Jim Brinkley
Date Deposited: 23 Jun 2018 04:41
Last Modified: 09 May 2019 23:35

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