Rosse, Cornelius and Mejino, Jose L V and Modayur, Bharath R and Jakobovits, Rex M and Hinshaw, Kevin P and Brinkley, James F (1998) Motivation and Organizational Principles for Anatomical Knowledge Representation: The Digital Anatomist Symbolic Knowledge Base. Journal of the American Medical Informatics Association, 5 (1). pp. 17-40.
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Abstract
Objective: Conceptualization of the physical objects and spaces that constitute the human body at the macroscopic level of organization, specified as a machine-parseable ontology which, in its human-readable form, is comprehensible to both expert and novice users of anatomical information.
Design: Conceived as an anatomical enhancement of the UMLS Semantic Network and Metathesaurus, the anatomical ontology was formulated by specifying defining attributes and differentia for classes and subclasses of physical anatomical entities based on their partitive and spatial relationships. The validity of the classification was assessed by instantiating the ontology for the thorax. Several transitive relationships were used for symbolically modeling aspects of the physical organization of the thorax.
Results: By declaring Organ as the macroscopic organizational unit of the body, and defining the entities that constitute organs and higher level entities constituted by organs, all anatomical entities could be assigned to one of three top level classes (Anatomical structure, Anatomical spatial entity and Body substance). The ontology accommodates both the systemic and regional (topographical) views of anatomy, as well as diverse clinical naming conventions of anatomical entities.
Conclusions: The ontology formulated for the thorax is extendible to microscopic and cellular levels, as well as to other body parts, in that its classes subsume essentially all anatomical entities that constitute the body. Explicit definitions of these entities and their relationships provide the first requirement for standards in anatomical concept representation. Conceived from an anatomical view point, the ontology can be generalized and mapped to other biomedical domains and problem solving tasks that require anatomical knowledge.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | anatomy|atlas96|braincr96|knowledge representation|mibook97|nihcv|sig|da99 |
| Subjects: | All Projects > Foundational Model of Anatomy |
| Depositing User: | Jim Brinkley |
| Date Deposited: | 01 May 2003 |
| Last Modified: | 27 Feb 2018 22:11 |
| URI: | http://sigpubs.si.washington.edu/id/eprint/96 |
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